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Anti-Mouse CD135 (Flt3) PE

Anti-Mouse CD135 (Flt3) PE

Item no.	17412-60-50
Manufacturer	BioGems
Amount	50 ug
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Flow Cytometry Primary Antibodies By Organ Bone Cancer
Type	Antibody
Format	PE
Applications	FC
Clone	A2F10
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a Kappa
Conjugate/Tag	PE
Citations	Hannum, C., Culpepper, J., Campbell, D., McClanahan, T., Zurawski, S., Kastelein, R., ... & Lee, F. (1994). Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs. Ogawa, M., Sugawara, S., Kunisada, T., Sudo, T., Hayashi, S. I., Nishikawa, S., & Kodama, H. (1998). Flt3/Flk-2 and c-Kit are not essential for the proliferation of B lymphoid progenitor cells in the bone marrow of the adult mouse. Experimental hematology, 26(6), 478-488. Matthews, W., Jordan, C. T., Wiegand, G. W., Pardoll, D., & Lemischka, I. R. (1991). A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations. Cell, 65(7), 1143-1152.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The A2F10 monoclonal antibody specifically reacts with mouse CD135, a tyrosine kinase class III receptor. CD135, also known as Flt3, Ly-72, and Flk-2, is the receptor for the FLT3 ligand (FLT3L) cytokine and is expressed on many hematopoietic progenitor cells. Signaling through CD135 plays a role in cell survival, proliferation, and differentiation. The A2F10 antibody is reported to inhibit the binding of FLT3L to CD135.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Stem Cell Research

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

17412-60-50-datasheet.pdf

17412-60-50-safety-datasheet.pdf