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AHR Polyclonal Antibody

AHR Polyclonal Antibody

Manufacturer	Biomatik
Category	Antibodies Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human
Amount	50ug
Host	Rabbit
Item no.	BM-CAC08217-50ug
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Isotype info	Recombinant human Aryl hydrocarbon receptor protein (126-353AA)
Immunogen	ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
Conjugation	Unconjugated
Alternative Names	Aryl hydrocarbon receptorAh receptorAhR, Class E basic helix-loop-helix protein 76, bHLHe76, AHR, BHLHE76
UniProt ID	P35869
Purification	>95%, Protein G purified
Storage	-20°C
Expiry Date	1 year
Shipping Condition	Ice packs
Comments	Conjugation service and the corresponding secondary antibody are available.
Technical Notes	Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
Restriction	For research use only. Not for diagnostic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ug

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Delivery expected until 5/30/2024