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ASIP Polyclonal Antibody

ASIP Polyclonal Antibody

Manufacturer	Biomatik
Category	Antibodies Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human
Amount	50ug
Host	Rabbit
Item no.	BM-CAC08249-50ug
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Isotype info	Recombinant human Agouti-signaling protein (23-112AA)
Immunogen	ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
Conjugation	Unconjugated
Alternative Names	Agouti-signaling proteinASP, Agouti switch protein, ASIP, AGTI, AGTIL, ASP
UniProt ID	P42127
Purification	>95%, Protein G purified
Storage	-20°C
Expiry Date	1 year
Shipping Condition	Ice packs
Comments	Conjugation service and the corresponding secondary antibody are available.
Technical Notes	Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). In higher primates, agouti may affect the quality of hair pigmentation rather than its pattern of deposition. Could well play a role in neuroendocrine aspects of melanocortin action. May have some functional role in regulating the lipid metabolism with adipocytes.
Restriction	For research use only. Not for diagnostic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ug

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Delivery expected until 5/30/2024