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EXO1 Polyclonal Antibody

EXO1 Polyclonal Antibody

Manufacturer	Biomatik
Category	Antibodies Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human
Amount	100ug
Host	Rabbit
Item no.	BM-CAC08414-100ug
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Isotype info	Recombinant human Exonuclease 1 protein (301-600AA)
Immunogen	ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200
Conjugation	Unconjugated
Alternative Names	Exonuclease 1, hExo1, Exonuclease I, hExoI, EXO1, EXOI, HEX1
UniProt ID	Q9UQ84
Purification	>95%, Protein G purified
Storage	-20°C
Expiry Date	1 year
Shipping Condition	Ice packs
Comments	Conjugation service and the corresponding secondary antibody are available.
Technical Notes	5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.
Restriction	For research use only. Not for diagnostic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 5/30/2024