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LIG3 Polyclonal Antibody

LIG3 Polyclonal Antibody

Manufacturer	Biomatik
Category	Antibodies Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human
Amount	50ug
Host	Rabbit
Item no.	BM-CAC08591-50ug
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Isotype info	Recombinant human DNA ligase 3 protein (809-928AA)
Immunogen	ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
Conjugation	Unconjugated
Alternative Names	DNA ligase 3, DNA ligase III, Polydeoxyribonucleotide synthase [ATP] 3, LIG3
UniProt ID	P49916
Purification	>95%, Protein G purified
Storage	-20°C
Expiry Date	1 year
Shipping Condition	Ice packs
Comments	Conjugation service and the corresponding secondary antibody are available.
Technical Notes	Isoform 3 functions as heterodimer with DNA-repair protein XRCC1 in the nucleus and can correct defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Isoform 1 is targeted to mitochondria, where it functions as DNA ligase in mitochondrial base-excision DNA repair (PubMed:10207110, PubMed:24674627).
Restriction	For research use only. Not for diagnostic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ug

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Delivery expected until 5/30/2024