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DNAJB6 Polyclonal Antibody

DNAJB6 Polyclonal Antibody

Manufacturer	Biomatik
Category	Antibodies Western Blot ELISA Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse
Applications	WB, IF, ELISA
Amount	50ug
Host	Rabbit
Item no.	BM-CAC08129-50ug
eClass 6.1	32160702
eClass 9.0	32160702
Available
Immunogen	Recombinant Human DnaJ homolog subfamily B member 6 protein (208-326AA)
Conjugate	Unconjugated
Alternative Names	DnaJ homolog subfamily B member 6, HHDJ1, Heat shock protein J2, HSJ-2, MRJ, MSJ-1, DNAJB6, HSJ2, MRJ, MSJ1
UniProt ID	O75190
Purification	Protein G purified, >95%
Storage Instructions	Aliquot and store at -20C. Minimize freezing and thawing.
Expiry Date	1 year
Shipping Condition	Blue ice
Comment	Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity.
Restriction	For research use only. Not for diagnostic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ug

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Delivery expected until 6/27/2024