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PPP2CA Polyclonal Antibody

PPP2CA Polyclonal Antibody

Manufacturer	Biomatik
Category	Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse
Amount	50ug
Host	Rabbit
Item no.	BM-CAC08752-50ug
Targets	PPP2CA
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Isotype info	Recombinant human Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform protein (1-309AA)
Immunogen	ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-5000, IHC:1:20-1:200, IF:1:50-1:200
Conjugation	Unconjugated
Alternative Names	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha, Replication protein C, RP-C, PPP2CA
UniProt ID	P67775
Purification	>95%, Protein G purified
Storage	-20°C
Expiry Date	1 year
Shipping Condition	Ice packs
Comments	Conjugation service and the corresponding secondary antibody are available.
Technical Notes	PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
Restriction	For research use only. Not for diagnostic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ug

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Delivery expected until 5/30/2024