Comparison

Sheep antibody to Connexin-37 (265-280): whole serum

Item no. S-062-100
Manufacturer Biosensis
Amount 100ul
Category
Type Antibody
Applications WB, IF
Specific against other
Host Sheep
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products Gja4, Gap junction alpha-4 protein, Cx37, Cxn-37
Available
Sub category
Receptors & Channel Molecules
products_extra_fields_value
FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low molecular weight diffuse from one cell to a neighboring cell. Connexin-37 may also mediate hyperexcitability followin nerve injury. SUBUNIT: A connexon is composed of a hexamer of connexins. SUBCELLULAR LOCATION: Membrane, multi-pass membrane protein. TISSUE SPECIFICITY: Highly expressed in lung. SIMILARITY: Belongs to the connexin family. Alpha-type (group II) subfamily.
products_quantity
200
storage
After reconstitution keep aliquots at -20AC for a higher stability, and at 4AC with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
purityisotype
Whole serum
formulation
Lyophilised
immunogen
A synthetic peptide (YLPMGE GPSSPPCPTY) as part of rat Connexin-37 protein (aa: 265-280) conjugated to diphtheria toxoid
crossreactivity
This antiserum recognises rat and mouse Connexin-37 protein.
conality
Sheep
specificity
Western blotting of cell membarnes of COS cells transiently transfected with cDNA encoding Connexin-37 shows two bands of molecular weight 36 and 37 kDa which are abolished by preincubation with the immunising peptide. No such bands are detected in western blots of membranes from non-transfected cells or cells transfected with cDNA encoding Connexin-40, Connexin-43 or Connexin-45.
reconstitution
Reconstitute in 100 Aul of sterile water. Centrifuge to remove any insoluble material.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ul
Available: In stock
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