alpha1- Antitrypsin

>95%

SERPIN1's primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. Short peptide from AAT: reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).

Serpin Family A Member 1, Serpin Peptidase Inhibitor, Clade A,

P01009

Store at -70C

Human Blood

Yes

5265

cool packs or dry ice

Mentioned in the data sheet

SERPINA1