Manufacturer |
Bioworld Technology, Inc
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Human |
Applications |
WB, IHC |
Amount |
50ul |
Host |
Rabbit |
Item no. |
BS3901-50 |
Targets |
FOXD3 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Swiss-Prot |
O60683 |
Application all |
WB: 1:500ca.1:1000 IHC: 1:50ca.1:200 |
Background |
The Peroxin gene family, which includes more than 20 members, is required for peroxisome biogenesis. Peroxin 10 (Peroxisome biogenesis factor 10), also known as RNF69 (RING finger protein 69), is a 326 amino acid protein that exhibits E3 ligase activity in vitro, suggesting that it is involved in Ubc4-dependent ubiquination. Defects in the gene encoding Peroxin 10 are the result of a number of different disorders, such as Peroxisome biogenesis disorder complementation group 7, Zellweger syndrome and adrenoleukodystrophy neonatal. There are two isoforms of Peroxin 10 that are produced as a result of alternative splicing events. |
Product |
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
Peroxin 10 (V215) pAb detects endogenous levels of Peroxin 10 protein. |
IHC |
Immunohistochemistry (IHC) analyzes of Peroxin 10 (V215) pAb in paraffin-embedded human breast cancer tissue. |
BiowMW |
ca. 42 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Peroxisome biogenesis factor 10, Peroxin-10, Peroxisomal biogenesis factor 10, Peroxisome assembly protein 10, RING finger protein 69, PEX10, RNF69 |
Immunogen |
Synthetic peptide, corresponding to amino acids 191-240 of Human Peroxin 10. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.