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Cytokeratin 15 Rabbit monoclonal antibody

Cytokeratin 15 Rabbit monoclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Neural Lineage Markers Antibodies Cell Biology Cytoskeleton Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies Intermediate filaments
Type	Antibody Monoclonal
Specific against	Human, Mouse
Applications	WB, FC, IHC
Amount	50ul
Host	Rabbit
Item no.	BS9947M-50
eClass 6.1	32160702
eClass 9.0	42030590
Available
Buffer composition	Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Background	Cytokeratin 15 is an intermediate filament (IF) type I protein that is responsible for the mechanical integrity of epithelial cells. Keratin family members are subdivided into cytokeratins and hair keratins. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceus. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins.
Application info	WB: 1:1, 000-1:2, 000 IHC/IF: 1:50-1:200 FC: 1:50-1:100
Swiss-Prot	P19012
Purification and Purity	Protein A affinity purified
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	This antibody detects endogenous levels of Cytokeratin 15 and does not cross-react with related proteins.
BiowMW	ca. 49 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Keratin, type I cytoskeletal 15, Cytokeratin-15, Short name=CK-15, Keratin-15, Short name=K15, KRT15, KRTB, Keratin 15, CK15, CK 15, Keratin15
Immunogen	Recombinant antibody.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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