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ACE (N-terminus) monoclonal antibody

ACE (N-terminus) monoclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Neural Lineage Markers Neuroinflammation Neural Mitochondrial Function Aging & Neurological Disorders Neural Signaling Infectious Diseases Viral Infections Antibodies Coronavirus Covid-19 Western Blot Cardiovascular Research Heart Failure Myocardial Infarction Primary Antibodies
Type	Antibody Monoclonal
Specific against	Human, Mouse
Applications	WB
Amount	100ul
Host	Mouse
Item no.	MB0114-100
Targets	ACE
eClass 6.1	32160702
eClass 9.0	42030590
Available
Swiss-Prot	P12821
Application all	WB:1:1000
Background	Angiotensin-converting enzyme (ACE) is a carboxy-terminal dipeptidyl exo-peptidase that converts Angiotensin I to the potent vasopressive hormone, Angiotensin II. There are two isoforms of ACE, the pulmonary ACEP and the testicular ACET. ACEP is a glycoprotein expressed in vascular endothelial cells of the lung, liver, adrenal cortex, pancreas, kidney and spleen. The ACET isoform is expressed exclusively in adult testis by developing sperm cells, specifically, late pachytene spermatocytes. Additionally, ACE inactivates bradykinin, a vasodepressor peptide, and is involved in fluid/electrolyte homeostasis.
Product	Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%, glycerol
Purification and Purity	The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	ACE (N-terminus) mAb detects endogenous levels of Angiotensin-converting enzyme protein.
WB	Western blot detection of ACE (N-terminus) antibody in Mouse kidney cell lysates using ACE (N-terminus) antibody (1:1000 diluted) .
BiowMW	Predicted band size:150KDa Observed band size:195KDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Angiotensin-converting enzyme, Short name=ACE, Dipeptidyl carboxypeptidase I, CD143, ACE1, DCP, DCP1, Angiotensin Converting Enzyme 1
Immunogen	Synthetic peptide, corresponding to the N-terminus of Human ACE.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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