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FGFR1 (R148) polyclonal antibody

FGFR1 (R148) polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Neuroinflammation Neural Adhesion Molecules Antibodies Cell Biology Cell Culture Cytokines Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Applications	WB, IF
Amount	100ul
Host	Rabbit
Item no.	BS3620-100
Targets	FGR ;;CD331;;FGF2;;TYK2
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	P11362
Application all	WB: 1:500ca.1:1000 IF: 1:50ca.1:200
Background	FGFR1 (fibroblast growth factor receptor 1) is a member of the fibroblast growth factor receptor family containing an Ig-like domain and a tyrosine kinase domain. This receptor has multiple isoforms and is a Type I membrane protein. FGFR1 is a widely expressed membrane receptor, with distinct isoforms expressed in specific tissues. FGFR1 binds fibroblast growth factor and induces mitogenesis and cellular differentiation. Defects in FGFR1 result in Pfeiffer syndrome associated with craniosynostosis. FGFR1 can be modified by phosphorylation and can bind basic/acidic fibroblast factor depending on the receptor isoform. FGFR1 has been shown to interact with N-cadherin and NCAM.
Product	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	FGFR1 (R148) pAb detects endogenous levels of FGFR1 protein.
BiowMW	ca. 120, 145 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Fibroblast growth factor receptor 1, FGFR-1, 2.7.10.1, Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1, Fms-like tyrosine kinase 2, FLT-2, N-sam, Proto-oncogene c-Fgr, CD331, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR, FGFR1
Immunogen	Synthetic peptide, corresponding to amino acids 118-160 of Human FGFR1.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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