Manufacturer |
Bioworld Technology, Inc
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat |
Applications |
WB, ICC |
Amount |
100ul |
Host |
Rabbit |
Item no. |
BS5760-100 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Swiss-Prot |
P13378 |
Application all |
WB: 1:500ca.1:1000 ICC: 1:50ca.1:200 |
Background |
The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxD8 (homeobox D8), also known as HOX4E, is a 290 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. One of several members of the homeobox superfamily, HoxD8 functions as a sequence-specific transcription factor that is important for the correct positioning of developing limb buds on the anterior-posterior axis. |
Product |
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
Hox-D8 pAb detects endogenous levels of Hox-D8 protein. |
WB |
Western blot (WB) analysis of Hox-D8 pAb at 1:500 dilution Lane1:Hela cell lysate Lane2:Raw264.7 cell lysate Lane3:H9C2 cell lysate |
BiowMW |
ca. 32 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Homeobox protein Hox-D8, Homeobox protein Hox-4E, Homeobox protein Hox-5.4, Name: HOXD8, HOX4E, Hox-5.4, |
Immunogen |
Synthetic peptide, corresponding to the 245-290 of Human Hox-D8. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.