Manufacturer |
Bioworld Technology, Inc
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat |
Applications |
WB, IF, IHC |
Amount |
50ul |
Host |
Rabbit |
Item no. |
BS6442-50 |
Targets |
PPARA ;;PPARG |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Swiss-Prot |
P37231 |
Application all |
WB: 1:500ca.1:2000 IHC/IF: 1:50ca.1:200 |
Background |
PPAR gamma is implicated in numerous diseases including obesity, diabetes, atherosclerosis and cancer. PPAR gamma activators include prostanoids, fatty acids, thiazolidinediones and N-(2-benzoylphenyl) tyrosine analogues. A key component in adipocyte differentiation and fat-specific gene expression, PPAR gamma may modulate macrophage functions such as proinflammatory activities, and stimulate oxidized low-density lipoprotein (x-LDL) uptake. |
Product |
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
PPARgamma pAb detects endogenous levels of PPARgamma protein. |
WB |
WesternBlot (WB) analysis of PPARgamma pAb in extracts from A549, DU145, PC3 and U937 cells. |
IHC |
Immunohistochemistry (IHC) analysis of PPARgamma pAb in paraffin-embedded H-ovary tissue. |
IF |
Immunofluorescence analysis of A549 cells, using PPARgamma polyclonal antibody |
BiowMW |
ca. 54 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Peroxisome proliferator-activated receptor gamma, Short name=PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, PPARG, NR1C3, PPAR gamma, PPARgamma |
Immunogen |
Recombinant full length Human PPARgamma. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.