Manufacturer |
Bioworld Technology, Inc
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat |
Applications |
WB, IF, IP, IHC, ICC |
Amount |
100ul |
Host |
Rabbit |
Item no. |
BS6572-100 |
Targets |
CTNND1 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Swiss-Prot |
O60716 |
Application all |
WB: 1:500ca.1:2000 IHC: 1:50ca.1:200 ICC/IF: 1:50ca.1:200 IP: 1:50ca.1:200 |
Background |
The alpha, beta, delta, and gamma -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. delta-catenin interacts with Presenilin 1 and is expressed in the brain. The gene encoding delta-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding delta-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. gamma-catenin, also known as plakoglobin, is an 80-88 kDa protein that binds alpha-catenin and N-cadherin. In addition, the transmembrane phosphatase PTPm associates with catenin/cadherin complexes and may regulate complex signaling. |
Product |
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
Catenin-delta1 pAb detects endogenous levels of Catenin-delta1 protein. |
WB |
Western blot analysis of Catenin-delta1 polyclonal antibody |
IF |
Immunofluorescence analysis of U2OS cells, using Catenin-delta1 polyclonal antibody |
BiowMW |
ca. 108 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Catenin delta1, Catenin delta-1, Cadherin-associated Src substrate, Short name=CAS, p120 catenin, p120(ctn), p120(cas), CTNND1, KIAA0384 |
Immunogen |
Recombinant full length Human Catenin-delta1. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.