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Anti-PAX6 Antibody (Center)

Anti-PAX6 Antibody (Center)

Item no.	BOS-A00273-1-80ul
Manufacturer	Boster
Amount	80 ul
Quantity options	400 ul 80 ul
Category	Neuroscience Neural Lineage Markers Neural Transcription Factors Molecular Targets for Neuroscience Neural Development Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence
Applications	WB, FC, IF, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Alias	Paired box protein Pax-6,Aniridia type II protein,Oculorhombin,PAX6,AN2
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight	46683 Da
Clonality	Polyclonal
Application Details	IF: 1:10-1:50 WB: 1:1000 IHC-P: 1:10-1:50 FC: 1:10-1:50
Gene Name	PAX6
Background	PAX6 is paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription.
Immunogen	This PAX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 183-210 amino acids from the Central region of human PAX6.
Contents	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Manufacturer - Research Category	Developmental Biology, Neuroscience, Signal Transduction
Protein Function	Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Acts as a transcriptional repressor of NFATC1- mediated gene expression (By similarity).
Subcellular Localization	Nucleus {ECO:0000250\|UniProtKB:P63015}. [Isoform 5a]: Nucleus {ECO:0000250\|UniProtKB:P63016}
Description	Boster Bio Anti-PAX6 Antibody (Center) (Catalog # A00273-1). Tested in WB, Flow Cytometry, IF, IHC-P application(s). This antibody reacts with Human.
Tissue Specificity	[Isoform 1]: Expressed in lymphoblasts.
Predicted Reactivity	Bovine, Mouse, Rat, Xenopus

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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BOS-A00273-1-80ul-datasheet.pdf

BOS-A00273-1-80ul-safety-datasheet.pdf