Anti-PAI-1 SERPINE1 Antibody

Primary Antibodies

45060 MW

WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200

Plasminogen activator inhibitor 1

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

1 mg/ml

Serine protease inhibitor. Inhibits TMPRSS7
(PubMed:15853774). Is a primary inhibitor of tissue-type
plasminogen activator (PLAT) and urokinase-type plasminogen
activator (PLAU). As PLAT inhibitor, it is required for
fibrinolysis down-regulation and is responsible for the controlled
degradation of blood clots (PubMed:8481516, PubMed:9207454,
PubMed:17912461). As PLAU inhibitor, it is involved in the
regulation of cell adhesion and spreading (PubMed:9175705). Acts
as a regulator of cell migration, independently of its role as
protease inhibitor (PubMed:15001579, PubMed:9168821). It is
required for stimulation of keratinocyte migration during
cutaneous injury repair (PubMed:18386027). It is involved in
cellular and replicative senescence (PubMed:16862142). Plays a
role in alveolar type 2 cells senescence in the lung (By
similarity). Is involved in the regulation of cementogenic
differentiation of periodontal ligament stem cells, and regulates
odontoblast differentiation and dentin formation during
odontogenesis (PubMed:25808697, PubMed:27046084).

Boster Bio Anti-PAI-1 SERPINE1 Antibody catalog # A00637. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Boster Bio Anti-PAI-1 SERPINE1 Antibody catalog # A00637. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.