Comparison

Anti-CNPase Antibody Picoband® European Partner

Item no. BOS-A01017-Biotin
Manufacturer Boster
Amount 100 ug/vial
Quantity options 100 ug/vial 10 ug 100 ug/vial 100 ug/vial 100 ug/vial 100 ug 100 ug 100 ug 100 ug/vial 100 ug/vial 100 ug/vial 100 ug/vial 100 ug/vial
Category
Type Antibody Polyclonal
Format Lyophilized
Applications WB, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Conjugate/Tag Biotin
Citations 1. Entrez Gene: CNP 2',3'-cyclic nucleotide 3' phosphodiesterase.
2. Hinman JD, Chen CD, Oh SY, Hollander W, Abraham CR (Jan 2008). Age-dependent accumulation of ubiquitinated 2',3'-cyclic nucleotide 3'-phosphodiesterase in myelin lipid rafts. Glia. 56 (1): 118–33.
3. Sprinkle TJ, Lanclos KD, Lapp DF (Jul 1992). Assignment of the human 2',3'-cyclic nucleotide 3'-phosphohydrolase gene to chromosome 17.Genomics. 13 (3): 877–80.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias 2',3'-cyclic-nucleotide 3'-phosphodiesterase,CNP,CNPase,3.1.4.37,CNP,
Available
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Molecular Weight
47 kDa
Calculated Molecular weight
47579 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
Gene Name
CNP
Gene Full Name
2', 3'-cyclic-nucleotide 3'-phosphodiesterase
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
2', 3'-Cyclic-nucleotide 3'-phosphodiesterase, also known as CNPase, is an enzyme that in humans is encoded by the CNP gene. And this gene is mapped to 17q21.2. CNPase is named for its ability to catalyze the phosphodiester hydrolysis of 2', 3'-cyclic nucleotides to 2'-nucleotides. CNPase is thought to play a critical role in the events leading up to myelination. Additionally, CNPase has been demonstrated to inhibit the replication of HIV-1 and other primate lentiviruses by binding the retroviral Gag protein and inhibiting the genesis of nascent viral particles.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human CNPase, identical to the related mouse sequence, and different from the related rat sequence by one amino acid.
Contents
Each vial contains 50% glycerol,  0.9% NaCl,  0.2% Na2HPO4,  0.02% NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
Cell Type Marker, Cell Type Markers, Neurodegenerative Disease, Neurology Process, Neuroscience, Tags & Cell Markers
Protein Name
2', 3'-cyclic-nucleotide 3'-phosphodiesterase
Protein Function
May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. .
Subcellular Localization
Membrane; Lipid-anchor. Melanosome. Firmly bound to membrane structures of brain white matter. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Description
Boster Bio Anti-CNPase Antibody Picoband® catalog # A01017. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Manufacturer - Cross Reactivity
No cross-reactivity with other proteins.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug/vial
Available: In stock
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