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Anti-HCRT Antibody

Anti-HCRT Antibody

Item no.	BOS-A01633-1-Biotin
Manufacturer	Boster
Amount	100 ug
Quantity options	100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Category	Metabolism Glucose Homeostasis Regulation of Appetite Obesity Immunohistochemistry Immunofluorescence
Format	Lyophilized
Applications	IF, IHC
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Biotin
Citations	1. Adamantidis, A. R., Zhang, F., Aravanis, A. M., Deisseroth, K., de Lecea, L. Neural substrates of awakening probed with optogenetic control of hypocretin neurons. Nature 450: 420-424, 2007. 2. Arii, J., Kanbayashi, T., Tanabe, Y., Sawaishi, Y., Kimura, S., Watanabe, A., Mishima, K., Hishikawa, Y., Shimizu, T., Nishino, S. CSF hypocretin-1 (orexin-A) levels in childhood narcolepsy and neurologic disorders. Neurology 63: 2440-2442, 2004. 3. Blouin, A. M., Thannickal, T. C., Worley, P. F., Baraban, J. M., Reti, I. M., Siegel, J. M. Narp immunostaining of human hypocretin (orexin) neurons: loss in narcolepsy. Neurology 65: 1189-1192, 2005.
Alias	70 kDa ribosomal protein S6 kinase 1 antibody,KS6B1_HUMAN antibody,p70 alpha antibody,P70 beta 1 antibody,p70 ribosomal S6 kinase alpha antibody,p70 ribosomal S6 kinase beta 1 antibody,p70 S6 kinase alpha antibody,P70 S6 Kinase antibody,p70 S6 kinase alpha 1 antibody,p70 S6 kinase alpha 2 antibody,p70 S6K antibody,p70 S6K-alpha antibody,p70 S6KA antibody,p70(S6K) alpha antibody,p70(S6K)-alpha antibody,p70-alpha antibody,p70-S6K 1 antibody,p70-S6K antibody,P70S6K antibody,P70S6K1 antibody,p70S6Kb antibody,PS6K antibody,Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody,Ribosomal protein S6 kinase beta 1 antibody,Ribosomal protein S6 kinase beta-1 antibody,Ribosomal protein S6 kinase I antibody,RPS6KB1 antibody,S6K antibody,S6K-beta-1 antibody,S6K1 antibody,Serine/threonine kinase 14 alpha antibody,Serine/threonine-protein kinase 14A antibody,STK14A antibody
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Observed Molecular weight	100, 150 kDa
Calculated Molecular weight	52588 MW
Clonality	Polyclonal
Application Details	Immunohistochemistry, 2-5 μg/ml, Mouse, Rat Immunofluorescence, 5 μg/ml, Mouse, Rat
Gene Name	HCRT
Gene Full Name	Serine/threonine-protein kinase AtPK1/AtPK6
Background	This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.
Immunogen	A synthetic peptide corresponding to a sequence in the middle region of human HCRT, identical to the related mouse and rat sequences.
Contents	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Purification	Immunogen affinity purified.
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Signal Transduction, Signaling Pathway, Small G Proteins
Protein Name	Serine/threonine-protein kinase AtPK1/AtPK6
Protein Function	Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway.
Subcellular Localization	Cytoplasm. Nucleus.
Description	Boster Bio Anti-HCRT Antibody Picoband® catalog # A01633-1. Tested in IF, IHC application. This antibody reacts with Mouse, Rat.
Tissue Specificity	Expressed in all tissues.
Manufacturer - Alias	70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Manufacturer - Cross Reactivity	No cross reactivity with other proteins.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A01633-1-Biotin-datasheet.pdf

BOS-A01633-1-Biotin-safety-datasheet.pdf