Anti-MCM7 Antibody

Primary Antibodies

81308 MW

WB 1:500-1:2000
IHC: 1:100-1:300
ELISA 1:20000
IF 1:50-200

DNA replication licensing factor MCM7

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

1 mg/ml

Acts as component of the MCM2-7 complex (MCM complex)
which is the putative replicative helicase essential for 'once per
cell cycle' DNA replication initiation and elongation in
eukaryotic cells. The active ATPase sites in the MCM2-7 ring are
formed through the interaction surfaces of two neighboring
subunits such that a critical structure of a conserved arginine
finger motif is provided in trans relative to the ATP-binding site
of the Walker A box of the adjacent subunit. The six ATPase active
sites, however, are likely to contribute differentially to the
complex helicase activity. Required for S-phase checkpoint
activation upon UV-induced damage.

Boster Bio Anti-MCM7 Antibody catalog # A01649-1. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.