Comparison

Anti-Xanthine Oxidase/XDH Antibody Picoband® European Partner

Item no. BOS-A01884-Fluoro594
Manufacturer Boster
Amount 100 ug/vial
Quantity options 100 ug/vial 10 ug 100 ug/vial 100 ug/vial 100 ug/vial 100 ug 100 ug 100 ug 100 ug/vial 100 ug/vial 100 ug/vial 100 ug/vial 100 ug/vial
Type Antibody Polyclonal
Format Lyophilized
Applications FC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Citations 1. Ichida K, Amaya Y, Noda K, Minoshima S, Hosoya T, Sakai O, Shimizu N, Nishino T (Nov 1993). Cloning of the cDNA encoding human xanthine dehydrogenase (oxidase): structural analysis of the protein and chromosomal location of the gene. Gene. 133 (2): 279–84.
2. Parzen SD, Fox AS (Dec 1964). Purification of xanthine dehydrogenase from drosophila melanogaster. BiochimicaetBiophysicaActa. 92: 465–71.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Xanthine dehydrogenase/oxidase,Xanthine dehydrogenase,XD,1.17.1.4,Xanthine oxidase,XO,1.17.3.2,Xanthine oxidoreductase,XOR,XDH,XDHA,
Available
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Calculated Molecular weight
146424 MW
Clonality
Polyclonal
Gene Name
XDH
Gene Full Name
Xanthine dehydrogenase/oxidase
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
Xanthine dehydrogenase, also known as XDH, is a protein that, in humans, is encoded by the XDH gene. Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.
Immunogen
E. coli-derived human Xanthine Oxidase recombinant protein (Position: T2-K343). Human Xanthine Oxidase shares 86.8% and 89.2% amino acid (aa) sequence identity with mouse and rat Xanthine Oxidase, respectively.
Contents
Each vial contains 50% glycerol,  0.9% NaCl,  0.2% Na2HPO4,  0.02% NaN3.
Purification
Immunogen affinity purified.
Manufacturer - Research Category
Cancer, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction
Protein Function
Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro). .
Subcellular Localization
Cytoplasm . Peroxisome . Secreted.
Tissue Specificity
Detected in milk (at protein level). .
Manufacturer - Cross Reactivity
No cross-reactivity with other proteins.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug/vial
Available: In stock
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