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Anti-Doppel/PRND Antibody Picoband™

Anti-Doppel/PRND Antibody Picoband™

Item no.	BOS-A05457-10ug
Manufacturer	Boster
Amount	10 ug
Quantity options	100 ug/vial 10 ug
Category	Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Primary
Format	Lyophilized
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Manufacturer - Category	Primary Antibodies, Rabbit Polyclonal Antibodies
Storage Conditions	Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Molecular Weight	23 kDa
Clonality	Polyclonal
Application Details	Western blot, 0.1-0.5μg/ml Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml
Gene Name	PRND
Gene Full Name	paraoxonase 1
Background	Prion protein 2 (dublet), also known as PRND, or Doppel protein, is a protein which in humans is encoded by the PRND gene. It is mapped to 20p13. This gene is found on chromosome 20, approximately 20 kbp downstream of the gene encoding cellular prion protein, to which it is biochemically and structurally similar. The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that is found predominantly in testis. Mutations in this gene may lead to neurological disorders.
Contents	Each vial contains 4 mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, 0.05 mg NaN₃.
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Neurodegenerative Disease, Neurology Process, Neuroscience
Protein Function	Required for normal acrosome reaction and for normal male fertility (By similarity). Can bind Cu (2+) (PubMed:15218028, PubMed:20411530).
Tissue Specificity	Expressed in testis, in Sertoli cells, ejaculated spermatozoa and in seminal fluid (at protein level).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A05457-10ug-datasheet.pdf

BOS-A05457-10ug-safety-datasheet.pdf