Comparison

Anti-TUBB2B Antibody (N-term) European Partner

Item no. BOS-A05849-400ul
Manufacturer Boster
Amount 400 ul
Quantity options 400 ul 80 ul
Category
Applications WB, IF, IHC-P
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Alias Tubulin beta-2B chain,TUBB2B
Available
Manufacturer - Applications
WB, IF, IHC-P-Leica
Manufacturer - Category
Primary Antibodies
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
49953 Da
Clonality
Polyclonal
Application Details
WB: 1:4000
IHC-P-Leica: 1:2000
IF: 1:10-1:50
Gene Name
TUBB2B
Background
The protein encoded by this gene is a beta isoform of
tubulin, which binds GTP and is a major component of microtubules.
This gene is highly similar to TUBB2A and TUBB2C. Defects in this
gene are a cause of asymmetric polymicrogyria. [provided by
RefSeq].
Immunogen
This TUBB2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of human TUBB2B.
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Manufacturer - Research Category
Signal Transduction
Protein Function
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:23001566, PubMed:28013290, PubMed:26732629). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. Plays a critical role in proper axon guidance in both central and peripheral axon tracts (PubMed:23001566). Implicated in neuronal migration (PubMed:19465910).
Subcellular Localization
Cytoplasm, cytoskeleton
Description
Boster Bio Anti-TUBB2B Antibody (N-term) (Catalog # A05849). Tested in WB, IF, IHC-P-Leica application(s). This antibody reacts with Human, Mouse, Rat.
Tissue Specificity
High expression in brain.
Predicted Reactivity
Chicken, Monkey, Bovine, Xenopus, Pig

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
available

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