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Anti-PARP10 Antibody Picoband®

Anti-PARP10 Antibody Picoband®

Item no.	BOS-A08514-2-Dylight550
Manufacturer	Boster
Amount	100 ug
Quantity options	100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Category	Oncology By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Flow Cytometry Western Blot ELISA Immunostaining
Format	Lyophilized
Applications	WB, FC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Dylight 550
Citations	1. Kleine, H., Poreba, E., Lesniewicz, K., Hassa, P. O., Hottiger, M. O., Litchfield, D. W., Shilton, B. H., Luscher, B. Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation. Molec. Cell 32: 57-69, 2008. 2. Lesniewicz, K., Luscher-Firzlaff, J., Poreba, E., Fuchs, P., Walsemann, G., Wiche, G., Luscher, B. Overlap of the gene encoding the novel poly(ADP-ribose) polymerase Parp10 with the plectin 1 gene and common use of exon sequences. Genomics 86: 38-46, 2005. 3. Yu, M., Schreek, S., Cerni, C., Schamberger, C., Lesniewicz, K., Poreba, E., Vervoorts, J., Walsemann, G., Grotzinger, J., Kremmer, E., Mehraein, Y., Mertsching, J., Kraft, R., Austen, M., Luscher-Firzlaff, J., Luscher, B. PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation. Oncogene 24: 1982-1993, 2005.
Alias	70 kDa ribosomal protein S6 kinase 1 antibody,KS6B1_HUMAN antibody,p70 alpha antibody,P70 beta 1 antibody,p70 ribosomal S6 kinase alpha antibody,p70 ribosomal S6 kinase beta 1 antibody,p70 S6 kinase alpha antibody,P70 S6 Kinase antibody,p70 S6 kinase alpha 1 antibody,p70 S6 kinase alpha 2 antibody,p70 S6K antibody,p70 S6K-alpha antibody,p70 S6KA antibody,p70(S6K) alpha antibody,p70(S6K)-alpha antibody,p70-alpha antibody,p70-S6K 1 antibody,p70-S6K antibody,P70S6K antibody,P70S6K1 antibody,p70S6Kb antibody,PS6K antibody,Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody,Ribosomal protein S6 kinase beta 1 antibody,Ribosomal protein S6 kinase beta-1 antibody,Ribosomal protein S6 kinase I antibody,RPS6KB1 antibody,S6K antibody,S6K-beta-1 antibody,S6K1 antibody,Serine/threonine kinase 14 alpha antibody,Serine/threonine-protein kinase 14A antibody,STK14A antibody
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Observed Molecular weight	140 kDa
Calculated Molecular weight	52588 MW
Clonality	Polyclonal
Application Details	Western blot, 0.25-0.5 μg/ml, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/ml
Gene Name	PARP10
Gene Full Name	Serine/threonine-protein kinase AtPK1/AtPK6
Background	Poly [ADP-ribose] polymerase 10 is an enzyme that in humans is encoded by the PARP10 gene. Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofactors.
Immunogen	E.coli-derived human PARP10 recombinant protein (Position: E14-E251). Human PARP10 shares 76.5% amino acid (aa) sequence identity with mouse PARP10.
Contents	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Purification	Immunogen affinity purified.
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Signal Transduction, Signaling Pathway, Small G Proteins
Protein Name	Serine/threonine-protein kinase AtPK1/AtPK6
Protein Function	Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway.
Subcellular Localization	Cytoplasm. Nucleus.
Description	Boster Bio Anti-PARP10 Antibody Picoband® catalog # A08514-2. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Expressed in all tissues.
Manufacturer - Alias	70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Manufacturer - Cross Reactivity	No cross reactivity with other proteins.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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BOS-A08514-2-Dylight550-datasheet.pdf

BOS-A08514-2-Dylight550-safety-datasheet.pdf