Comparison

Anti-RAB39A/B Antibody Picoband® European Partner

Item no. BOS-A11551-1-PE
Manufacturer Boster
Amount 100 ug
Quantity options 100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Category
Format Lyophilized
Applications WB, FC, IF, ICC, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Conjugate/Tag PE
Citations 1. Becker, C. E., Creagh, E. M., O'Neill, L. A. J. Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1-beta secretion. J. Biol. Chem. 284: 34531-34537, 2009. Note: Erratum: J. Biol. Chem. 291: 24800 only, 2016.
2. Cruz, F. M., Colbert, J. D., Rock, K. L. The GTPase Rab39a promotes phagosome maturation into MHC-I antigen-presenting compartments. EMBO J. 39: e102020, 2020.
3. Gross, M. B. Personal Communication. Baltimore, Md. 10/1/2021.
Alias Interleukin-17B,IL-17B,Cytokine CX1,Cytokine-like protein ZCYTO7,Neuronal interleukin-17-related factor,Il17b,Nirf,Zcyto7
Available
Manufacturer - Category
Primary Antibodies
Storage Conditions
At -20°C for one year from date of receipt.
After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.
Avoid repeated freezing and thawing.
Observed Molecular weight
20-24 kDa
Clonality
Polyclonal
Application Details
Western blot, 0.25-0.5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x1x106 cells, Human
ELISA, 0.1-0.5 μg/ml
Gene Name
RAB39A/B
Gene Full Name
interleukin 17B
Background
This gene encodes a protein which is a member of the Rab family.The Rab family of proteins is a member of the Ras superfamily of monomeric G proteins. Approximately 70 types of Rabs have now been identified in humans. Rab GTPases regulate many steps of membrane traffic, including vesicle formation, vesicle movement along actin and tubulin networks, and membrane fusion. These processes make up the route through which cell surface proteins are trafficked from the Golgi to the plasma membrane and are recycled. Surface protein recycling returns proteins to the surface whose function involves carrying another protein or substance inside the cell, such as the transferrin receptor, or serves as a means of regulating the number of a certain type of protein molecules on the surface.
Immunogen
E.coli-derived human RAB39A/B recombinant protein (Position: M1-C217).
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Purification
Immunogen affinity purified.
Reconstitution
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
Cytokines, Immunology, Innate Immunity, Interleukins
Protein Function
Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1.
Subcellular Localization
Secreted.
Description
Boster Bio Anti-RAB39A/B Antibody Picoband® catalog # A11551-1. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.
Manufacturer - Cross Reactivity
No cross-reactivity with other proteins.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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