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Anti-FoxO3a Rabbit Monoclonal Antibody

Anti-FoxO3a Rabbit Monoclonal Antibody

Item no.	BOS-M00252-30ul
Manufacturer	Boster
Amount	30 ul
Quantity options	100 ul 30 ul
Category	Oncology Antibodies By Cell Type Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies Immunochemistry
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, ICC
Clone	HFD-6
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<10 pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Forkhead box protein O3,AF6q21 protein,Forkhead in rhabdomyosarcoma-like 1,FOXO3,FKHRL1,FOXO3A
Available
Manufacturer - Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	80 kDa
Calculated Molecular weight	71277 MW
Clonality	Monoclonal
Application Details	WB 1:1000-1:2000 ICC/IF 1:50-1:200
Gene Name	FOXO3
Gene Full Name	Forkhead box protein O3
Immunogen	A synthesized peptide derived from human FoxO3a
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Apoptosis, Associated Proteins, Cancer, Cell Biology, Co-Activators/Co-Repressors, Domain Families, Epigenetics and Nuclear Signaling, Forkhead Box, Hypoxia, Intracellular, Metabolism, Metabolism Processes, Nuclear Receptors, Nuclear Signaling Pathways, Oncoproteins, Oncoproteins/Suppressors, Pathways and Processes, Transcription, Transcription Factors
Protein Name	P2X purinoceptor 1
Protein Function	Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post- transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
Subcellular Localization	Cytoplasm, cytosol. Nucleus. Translocates to the nucleus upon oxidative stress and in the absence of survival factors.
Description	Boster Bio Anti-FoxO3a Rabbit Monoclonal Antibody catalog # M00252. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Ubiquitous.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M00252-30ul-datasheet.pdf

BOS-M00252-30ul-safety-datasheet.pdf