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Anti-PPARA Antibody

Anti-PPARA Antibody

Item no.	BOS-M00600-80ul
Manufacturer	Boster
Amount	80 ul
Quantity options	400 ul 80 ul
Category	Metabolism Diabetes Glucose Homeostasis Antibodies Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Cardiovascular Research Atherosclerosis
Type	Antibody Monoclonal
Applications	WB, FC, IF, IHC-P
Clone	1331CT894.186.143
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG1 Kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Peroxisome proliferator-activated receptor alpha,PPAR-alpha,Nuclear receptor subfamily 1 group C member 1,PPARA,NR1C1,PPAR
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight	52225 Da
Clonality	Monoclonal
Application Details	IF: 1:25 WB: 1:1000 IHC-P: 1:25 FC: 1:25
Gene Name	PPARA
Background	Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl- 2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.
Immunogen	This PPARA antibody is generated from a mouse immunized with a recombination protein from the human region of human PPARA.
Contents	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification	This antibody is purified through a protein G column, followed by dialysis against PBS.
Manufacturer - Research Category	Cancer, Cardiovascular, Metabolism, TLR Signaling
Protein Function	Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn- glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
Subcellular Localization	Nucleus.
Description	Boster Bio Anti-PPARA Antibody (Catalog # M00600). Tested in IHC-P, IF, Flow Cytometry, WB application(s). This antibody reacts with Human, Mouse.
Tissue Specificity	Skeletal muscle, liver, heart and kidney. Expressed in monocytes (PubMed:28167758).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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BOS-M00600-80ul-datasheet.pdf

BOS-M00600-80ul-safety-datasheet.pdf