Anti-PBRM1 Rabbit Monoclonal Antibody

Item no.	BOS-M01130-30ul
Manufacturer	Boster
Amount	30 ul
Quantity options	100 ul 30 ul
Category	Oncology Assisted reproductive technologies Embryo manipulation Antibodies By Cell Type Carcinoma Melanoma Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies Immunochemistry
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, FC, IF, IHC, ICC
Clone	AFHG-16
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<20 pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	14-3-3 protein sigma,Epithelial cell marker protein 1,Stratifin,SFN,HME1
Available
Manufacturer - Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	80 kDa
Calculated Molecular weight	27774 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:2000 IHC 1:100-1:500 ICC/IF 1:50-1:100 FC 1:50
Gene Name	PBRM1
Gene Full Name	14-3-3 protein sigma
Immunogen	A synthesized peptide derived from human PBRM1
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Chromatin Remodeling, Domain Families, Epigenetics and Nuclear Signaling, Transcription
Protein Name	Glycogen synthase kinase-3 beta (gsk3b)
Protein Function	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.
Subcellular Localization	Cytoplasm. Nucleus. Secreted. May be secreted by a non-classical secretory pathway.
Description	Boster Bio Anti-PBRM1 Rabbit Monoclonal Antibody catalog # M01130. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Present mainly in tissues enriched in stratified squamous keratinizing epithelium.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M01130-30ul-datasheet.pdf

BOS-M01130-30ul-safety-datasheet.pdf