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Anti-Prostaglandin E Receptor EP2/PTGER2 Antibody Picoband®

Anti-Prostaglandin E Receptor EP2/PTGER2 Antibody Picoband®

Item no.	BOS-PB9386-carrier-free
Manufacturer	Boster
Amount	100 ug
Quantity options	100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Category	Oncology Antibodies Western Blot Primary Antibodies By Organ Lung Cancer
Type	Antibody Polyclonal
Format	Lyophilized
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Sensitivity	<10 pg/ml
Sequence	Belongs to the G-protein coupled receptor 1 family.
Citations	1. Smock, S. L., Pan, L. C., Castleberry, T. A., Lu, B., Mather, R. J., Owen, T. A. Cloning, structural characterization, and chromosomal localization of the gene encoding the human prostaglandin E2 receptor EP2 subtype. Gene 237: 393-402, 1999. 2. Sugimoto Y, Nakato T, Kita A et al. (2004). A cluster of aromatic amino acids in the i2 loop plays a key role for Gs coupling in prostaglandin EP2 and EP3 receptors. J. Biol. Chem. 279 (12): 11016–26.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Prostaglandin E2 receptor EP2 subtype,PGE receptor EP2 subtype,PGE2 receptor EP2 subtype,Prostanoid EP2 receptor,PTGER2
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Conjugate / Tag	carrier-free
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	40 kDa
Calculated Molecular weight	39761 MW
Clonality	Polyclonal
Application Details	Western blot, 0.1-0.5μg/ml, Human
Gene Name	PTGER2
Gene Full Name	Prostaglandin E2 receptor EP2 subtype
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	Prostaglandin E2 receptor (53kDa), also known as EP2, is aprostaglandin receptor for prostaglandin E2. It is encoded by the human gene PTGER2. It may be associated with aspirin-induced asthma. PTGER2 is mapped to chromosome 14q22. This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma.
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of human PTGER2, different from the related mouse sequence by four amino acids, and from the related rat sequence by three amino acids.
Contents	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	G Protein Signaling, Lipid Signaling, Signal Transduction, Signaling Pathway
Protein Name	Prostaglandin E2 receptor EP2 subtype
Protein Function	Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G (s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.
Subcellular Localization	Cell membrane; Multi-pass membrane protein.
Description	Boster Bio Anti-Prostaglandin E Receptor EP2/PTGER2 Antibody Picoband® catalog # PB9386. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Placenta and lung.
Sequence Similarities	Belongs to the G-protein coupled receptor 1 family.
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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BOS-PB9386-carrier-free-datasheet.pdf

BOS-PB9386-carrier-free-safety-datasheet.pdf