Comparison

Anti-SOX1 Antibody Picoband® European Partner

Item no. BOS-PB9403-Dylight594
Manufacturer Boster
Amount 100 ug
Quantity options 100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Category
Type Antibody Polyclonal
Format Lyophilized
Applications WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Conjugate/Tag DyLight 594
Sensitivity >5000 cells
Sequence Belongs to the Cu-Zn superoxide dismutase family.
Citations 1. Guth SI, Wegner M (October 2008). Having it both ways: Sox protein function between conservation and innovation. Cell. Mol. Life Sci. 65 (19): 3000–18.
2. Jump up^ Nitta KR, Takahashi S, Haramoto Y, Fukuda M, Onuma Y, Asashima M (December 2006). Expression of Sox1 during Xenopus early embryogenesis. Biochem. Biophys. Res. Commun. 351 (1): 287–93.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Transcription factor SOX-1,SOX1
Available
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight
39 kDa
Calculated Molecular weight
39023 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5μg/ml, Mouse, Rat, Human
Gene Name
SOX1
Gene Full Name
Transcription factor SOX-1
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
SOX1 (for Sex determining region Y-box 1), located in 13q34, is a transcription factor in the Sox protein family. It means that this intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. SOX1 expression is restricted to neuroectodermin the tetrapod embryo. It is expressed particularly in the ventral striatum.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of Human SOX1, identical to the related mouse sequence.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
Developmental Families, Domain Families, Epigenetics and Nuclear Signaling, Intracellular, Neural Stem Cells, Neurogenesis, Neurology Process, Neuroscience, Stem Cells, Transcription
Protein Name
Transcription factor SOX-1
Protein Function
Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Subcellular Localization
Nucleus.
Description
Boster Bio Anti-SOX1 Antibody Picoband® catalog # PB9403. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Mainly expressed in the developing central nervous system.
Sequence Similarities
Belongs to the Cu-Zn superoxide dismutase family.
Manufacturer - Cross Reactivity
No cross-reactivity with other proteins.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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