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Anti-Wnt1 Antibody Picoband®

Anti-Wnt1 Antibody Picoband®

Item no.	BOS-PB9460-HRP
Manufacturer	Boster
Amount	100 ug
Quantity options	100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Category	Oncology Antibodies By Cell Type Carcinoma Adenocarcinoma Western Blot Primary Antibodies By Organ Brain Cancer
Type	Antibody Polyclonal
Format	Lyophilized
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	HRP
Sensitivity	>5000 cells
Sequence	Belongs to the Wnt family.
Citations	1. Arheden K, Mandahl N, Strombeck B, Isaksson M, Mitelman F (May 1988). Chromosome localization of the human oncogene INT1 to 12q13 by in situ hybridization. Cytogenet Cell Genet 47 (1–2): 86–87. 2. Entrez Gene: WNT1 wingless-type MMTV integration site family, member 1. 3. Van Ooyen A, Kwee V, Nusse R (Jan 1986). The nucleotide sequence of the human int-1 mammary oncogene; evolutionary conservation of coding and non-coding sequences. EMBO J 4 (11): 2905–9.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Proto-oncogene Wnt-1,Proto-oncogene Int-1 homolog,WNT1,INT1
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	45 kDa
Calculated Molecular weight	40982 MW
Clonality	Polyclonal
Application Details	Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
Gene Name	WNT1
Gene Full Name	Proto-oncogene Wnt-1
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	Wingless-type MMIV integration site family, member 1 is a protein that in humans is encoded by the WNT1 gene. This gene is a member of the WNT gene family. The gene was assigned to human chromosome 12q13.12. The WNT gene family consists of structurally related genes that encode secreted signaling proteins. The Wnt1 protein functions in the induction of the mesencephalon and cerebellum. However, the gene mutations might not have a significant role in Joubert syndrome.
Immunogen	A synthetic peptide corresponding to a sequence at the N-terminus of human Wnt1, identical to the related mouse and rat sequences.
Contents	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Cancer, Oncoproteins/Suppressors, Secreted, Signaling Pathways, Stem Cells, Surface Molecules, Tumor Suppressors
Protein Name	Proto-oncogene Wnt-1
Protein Function	Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters. Has a role in osteoblast function and bone development.
Subcellular Localization	Secreted, extracellular space, extracellular matrix.
Description	Boster Bio Anti-Wnt1 Antibody Picoband® catalog # PB9460. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Expressed predominantly in the thymus. Also found, to a much lesser extent, in the spleen.
Sequence Similarities	Belongs to the Wnt family.
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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BOS-PB9460-HRP-datasheet.pdf

BOS-PB9460-HRP-safety-datasheet.pdf