Comparison

Anti-Rab18 Antibody Picoband® European Partner

Item no. BOS-PB9791-Dylight594
Manufacturer Boster
Amount 100 ug
Quantity options 100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Category
Type Antibody Polyclonal
Format Lyophilized
Applications WB
Specific against Human (Homo sapiens), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Conjugate/Tag DyLight 594
Sensitivity >5000 cells
Citations 1. Entrez Gene: RAB18 RAB18, member RAS oncogene family.
2. Lütcke A, Parton RG, Murphy C, Olkkonen VM, Dupree P, Valencia A, Simons K, Zerial M (December 1994). Cloning and subcellular localization of novel rab proteins reveals polarized and cell type-specific expression. J. Cell. Sci. 107 (12): 3437–48.
3. Schafer U, Seibold S, Schneider A, Neugebauer E (Feb 2000). Isolation and characterisation of the human rab18 gene after stimulation of endothelial cells with histamine. FEBS Lett 466 (1): 148–54.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Ras-related protein Rab-18,RAB18
Available
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight
23 kDa
Calculated Molecular weight
22977 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5μg/ml, Human, Rat
Gene Name
RAB18
Gene Full Name
Ras-related protein Rab-18
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
Ras-related protein Rab-18 is a protein that in humans is encoded by the RAB18 gene. It is a ubiquitously expressed protein with particularly high expression in the brain. The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies in zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Rab18, identical to the related mouse sequence, and different from the related rat sequence by one amino acid.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
G Protein Signaling, Protein Trafficking, Ras Family, Signal Transduction, Signaling Pathway, Small G Proteins, Vesicle Transport
Protein Name
Ras-related protein Rab-18
Protein Function
Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes. Plays a key role in eye and brain development and neurodegeneration.
Subcellular Localization
Cell membrane; Lipid-anchor; Cytoplasmic side.
Description
Boster Bio Anti-Rab18 Antibody Picoband® catalog # PB9791. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Ubiquitous.
Manufacturer - Cross Reactivity
No cross-reactivity with other proteins.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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