Comparison

Anti-EPCR/CD201/PROCR Antibody Picoband® European Partner

Item no. BOS-PB9880-APC
Manufacturer Boster
Amount 100 ug
Quantity options 100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Category
Type Antibody Polyclonal
Format Lyophilized
Applications WB, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Conjugate/Tag APC
Sensitivity <20 pg/ml
Citations 1. Entrez Gene: PROCR protein C receptor, endothelial (EPCR).
2. Fukudome K, Esmon CT (Nov 1994). Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptor. J Biol Chem 269 (42): 26486–91.
3. Rothbarth K, Dabaghian AR, Stammer H, Werner D (Oct 1999). One single mRNA encodes the centrosomal protein CCD41 and the endothelial cell protein C receptor (EPCR). FEBS Lett 458 (1): 77–80.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Endothelial protein C receptor,Activated protein C receptor,APC receptor,Endothelial cell protein C receptor,CD201,PROCR,EPCR
Available
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight
46 kDa, 52 kDa
Calculated Molecular weight
26671 MW
Clonality
Polyclonal
Application Details
ELISA, 0.1-0.5μg/ml, -
Western blot, 0.1-0.5μg/ml, Human
Gene Name
PROCR
Gene Full Name
Endothelial protein C receptor
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor), is a protein that in humans is encoded by the PROCR gene. It has also recently been designated CD201 (cluster of differentiation 201). The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. And it is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer.
Immunogen
E. coli-derived human EPCR/CD201 recombinant protein (Position: S18-S210). Human EPCR/CD201 shares 65.5% and 65.6% amino acid (aa) sequence identity with mouse and rat EPCR/CD201, respectively.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
Cardiovascular, Hematopoietic Progenitors, Stem Cells, Vasculature
Protein Name
Endothelial protein C receptor
Protein Function
Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
Subcellular Localization
Membrane; Single-pass type I membrane protein.
Description
Boster Bio Anti-EPCR/CD201/PROCR Antibody Picoband® catalog # PB9880. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?