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Anti-ALDH3A1 Antibody Picoband® European Partner

Item no. BOS-PA2074
Manufacturer Boster
Amount 100 ug/vial
Category
Type Antibody Polyclonal
Format Lyophilized
Applications WB, IHC
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Sensitivity >5000 cells
Citations 1. Hiraoka, L. R., Hsu, L., Hsieh, C.-L. Assignment of ALDH3 to human chromosome 17p11.2 and ALDH5 to human chromosome 9p13. Genomics 25: 323-325, 1995.
2. Santisteban, I., Povey, S., West, L. F., Parrington, J. M., Hopkinson, D. A. Chromosome assignment, biochemical and immunological studies on a human aldehyde dehydrogenase, ALDH3. Ann. Hum. Genet. 49: 87-100, 1985.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Aldehyde dehydrogenase, dimeric NADP-preferring;1.2.1.5;ALDHIII;Aldehyde dehydrogenase 3;Aldehyde dehydrogenase family 3 member A1;ALDH3A1;ALDH3;
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Available
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
50 kDa
Calculated Molecular weight
50395 MW
Clonality
Polyclonal
Application Details
Immunohistochemistry (Paraffin-embedded Section), 2-5?g/ml, Human, By Heat
Western blot, 0.1-0.5?g/ml, Human
Manufacturer - Gene Name
ALDH3A1
Gene Full Name
Aldehyde dehydrogenase, dimeric NADP-preferring
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
ALDH3A1 (Aldehyde Dehydrogenase, Family 3, Subfamily A, Member 1), also known as ALDH3, is an enzyme that in humans is encoded by the ALDH3A1 gene. By in situ hybridization, Hiraoka et al. (1995) mapped the ALDH3 gene to 17p11.2. ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human ALDH3A1.
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Cancer, Cell Biology, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Neuroscience, Oxidative Stress, Pathways and Processes, Redox Metabolism, Sensory System, Signal Transduction, Visual System
Protein Name
Aldehyde dehydrogenase, dimeric NADP-preferring
Protein Function
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.
Subcellular Localization
Cytoplasm.
Description
Boster Bio Anti-ALDH3A1 Antibody catalog # PA2074. Tested in IHC, WB applications. This antibody reacts with Human.
Tissue Specificity
High levels in stomach, esophagus and lung; low level in the liver and kidney.
Sequence Similarities
Belongs to the aldehyde dehydrogenase family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug/vial
Available: In stock
available

Delivery expected until 10/2/2025 

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