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Anti-MCP4/CCL13 Antibody Picoband™

Anti-MCP4/CCL13 Antibody Picoband™

Manufacturer	Boster
Category	Oncology Neuroscience Neuroinflammation Antibodies Western Blot ELISA Primary Antibodies By Organ Colorectal Cancer
Type	Antibody Polyclonal
Specific against	Human
Isotype	IgG
Format	Lyophilized
Applications	WB, ELISA
Amount	100 ug/vial
Host	Rabbit
Item no.	BOS-PB9030
Targets	CXCR1
eClass 6.1	32160702
eClass 9.0	32160702
Available
Manufacturers Product Category	Primary Antibodies, Rabbit Polyclonal Antibodies
Manufacturers Research Category	Chemokines, Immunology, Innate Immunity, Macrophage/Inflammation
Short Description	Boster Bio Anti-MCP4/CCL13 Antibody Picoband™ catalog # PB9030. Tested in ELISA, WB applications. This antibody reacts with Human.
Description	Boster Bio Anti-MCP4/CCL13 Antibody Picoband™ catalog # PB9030. Tested in ELISA, WB applications. This antibody reacts with Human.
Background	Chemokine (C-C motif) ligand 13 (CCL13) is a small cytokine belonging to the CC chemokine family. Its gene is located on human chromosome 17 within a large cluster of other CC chemokines. CCL13 induces chemotaxis in monocytes, eosinophils, T lymphocytes, and basophils by binding cell surface G-protein linked chemokine receptors such as CCR2, CCR3 and CCR5. Activity of this chemokine has been implicated in allergic reactions such as asthma. CCL13 can be induced by the inflammatory cytokines interleukin-1 and TNF-alpha.
Gene Name	CCL13
Application Details	Western blot, 0.1-0.5μg/ml, Human, - ELISA , 0.1-0.5μg/ml, Human
Application Notes	WB: The detection limit for MCP4 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Clonality	Polyclonal
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Contents	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen	E.coli-derived human MCP4 recombinant protein (Position: Q24-T98).
Purification	Immunogen affinity purified.
Cross-reactivity	No cross-reactivity with other proteins
Storage	Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Gene Full Name	C-C motif chemokine 13
Molecular Weight	10986 MW
Protein Function	Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.
Subcellular Localization	Secreted.
Tissue Specificity	Widely expressed. Found in small intestine, thymus, colon, lung, trachea, stomach and lymph node. Low levels seen in the pulmonary artery smooth muscle cells.
Protein Name	C-C motif chemokine 13
Sequence Similarities	Belongs to the intercrine beta (chemokine CC) family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.