Comparison

Anti-Retinal dehydrogenase 1 ALDH1A1 Antibody Picoband® European Partner

Item no. BOS-PA1671
Manufacturer Boster
Amount 100 ug/vial
Category
Type Antibody Polyclonal
Format Lyophilized
Applications WB, FC, IF, IHC, ICC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity <10pg/ml
Citations 1. Eckey, R., Agarwal, D. P., Saha, N., Goedde, H. W. Detection and partial characterization of a variant form of cytosolic aldehyde dehydrogenase isozyme. Hum. Genet. 72: 95-97, 1986.
2. Hempel, J., von Bahr-Lindstrom, H., Jornvall, H. Aldehyde dehydrogenase from human liver: primary structure of the cytoplasmic isoenzyme. Europ. J. Biochem. 141: 21-35, 1984.
3. Pereira F, Rosenmann E, Nylen E, Kaufman M, Pinsky L, Wrogemann K (March 1991). "The 56 kDa androgen binding protein is an aldehyde dehydrogenase". Biochem. Biophys. Res. Commun. 175 (3): 831–8.

ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Retinal dehydrogenase 1;RALDH 1;RalDH1;1.2.1.36;ALDH-E1;ALHDII;Aldehyde dehydrogenase family 1 member A1;Aldehyde dehydrogenase, cytosolic;ALDH1A1;ALDC, ALDH1, PUMB1;
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Available
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
65 kDa
Calculated Molecular weight
54862 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5 ?g/ml, Human, Mouse, Rat
,
Immunohistochemistry (Paraffin-embedded Section), 2-5 ?g/ml, Human, By Heat

Immunocytochemistry/Immunofluorescence, 5 ?g/ml, Human

Flow Cytometry(Fixed), 1-3 ?g/1x106 cells, Human
Manufacturer - Gene Name
ALDH1A1
Gene Full Name
Retinal dehydrogenase 1
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
ALDH1A1 (Aldehyde dehydrogenase 1 family, member A1), also called ALDH1, RALDH1 or ALDH, LIVER CYTOSOLIC, is an enzyme that in humans is encoded by the ALDH1A1 gene. And this protein belongs to the aldehyde dehydrogenases family of proteins. The ALDH1A1 gene is mapped on 9q21.13. ALDH1A1 also belongs to the group of corneal crystallins that help maintain the transparency of the cornea.ALDH1A1 is associated with a low Km for NAD, a high Km for acetaldehyde, and is strongly inactivated by disulfiram. The ALDH1 gene is about 53 kb long and is divided into 13 exons. Retinaldehyde is generated by ADH1 from retinol, and its concentration is determined in large part by its subsequent catabolism by RALDH1 to retinoic acid.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human ALDH1A1, different from the related rat and mouse sequences by one amino acid.
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Cancer, Cell Type Marker, Hematopoietic Progenitors, Neurodegenerative Disease, Neurogenesis, Neurology Process, Neuron Marker, Neuroscience, Stem Cells, Tumor Biomarkers
Protein Name
Retinal dehydrogenase 1(RALDH 1/RalDH1)
Protein Function
Binds free retinal and cellular retinol-binding protein- bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity).
Subcellular Localization
Cytoplasm.
Description
Boster Bio Anti-Retinal dehydrogenase 1 ALDH1A1 Antibody catalog # PA1671. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Sequence Similarities
Belongs to the aldehyde dehydrogenase family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug/vial
Available: In stock
available

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