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Anti-CD80 Antibody Picoband™

Anti-CD80 Antibody Picoband™

Manufacturer	Boster
Category	Neuroscience Neural Lineage Markers Antibodies Immunohistochemistry ELISA Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Rat
Isotype	IgG
Format	Lyophilized
Applications	IHC, ELISA
Amount	100 ug/vial
Host	Rabbit
Item no.	BOS-A00196-1
eClass 6.1	32160702
eClass 9.0	32160702
Available
Manufacturers Product Category	Primary Antibodies, Rabbit Polyclonal Antibodies
Manufacturers Research Category	Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunology, Lymphoid, Myeloid, Stem Cells
Short Description	Boster Bio Anti-CD80 Antibody Picoband™ catalog # A00196-1. Tested in ELISA, IHC applications. This antibody reacts with Human, Rat.
Description	Boster Bio Anti-CD80 Antibody Picoband™ catalog # A00196-1. Tested in ELISA, IHC applications. This antibody reacts with Human, Rat.
Background	Cluster of Differentiation 80 (also CD80 and B7-1) is a protein found on activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells. The CD80 genes encode B7-1 which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types.
Gene Name	CD80
Application Details	Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml Direct ELISA, 0.1-0.5μg/ml
Clonality	Polyclonal
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Contents	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Immunogen	E. coli-derived human CD80 recombinant protein (Position: V35-L244).
Storage	Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Gene Full Name	CD80 molecule
Protein Function	Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.
Subcellular Localization	Membrane; Single-pass type I membrane protein.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug/vial

available

Delivery expected until 6/13/2024