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Anti-PCK Antibody (Monoclonal, C-11+PCK-26+CY-90+KS-1A3+M20+A53-B/A2)

Anti-PCK Antibody (Monoclonal, C-11+PCK-26+CY-90+KS-1A3+M20+A53-B/A2)

Item no.	BOS-MA1081
Manufacturer	Boster
Amount	100 ug/vial
Quantity options	100 ug/vial 10 ug
Category	Oncology Neuroscience Neural Lineage Markers Antibodies Immunohistochemistry Western Blot Primary Antibodies By Organ Nervous System Cancer
Type	Antibody Monoclonal
Format	Lyophilized
Applications	WB, IHC
Clone	C-11+PCK-26+CY-90+KS-1A3+M20+A53-B/A2
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1, IgG2a
Sensitivity	<10 pg/ml
Sequence	Belongs to the intermediate filament family.
Citations	1. Rastaldi MP et al. Glomerular podocytes contain neuron-like functional synaptic vesicles. FASEB J 20:976-8 (2006). 2. Wen J et al. Use of superparamagnetic microbeads in tracking subretinal injections. Mol Vis 11:256-62 (2005).
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Keratin,type II cytoskeletal 1,67 kDa cytokeratin,Cytokeratin-1,CK-1,Hair alpha protein,Keratin-1,K1,Type-II keratin Kb1,KRT1,KRTA
Similar products	PCK
Available
Manufacturer - Category	Primary Antibodies, Mouse Monoclonal Antibodies
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	45-60 kDa
Calculated Molecular weight	66039 MW
Clonality	Monoclonal
Application Details	Immunohistochemistry (Paraffin-embedded Section), 0.1-0.5μg/ml, Human, rat Immunohistochemistry (Frozen Section), 0.1-0.5μg/ml, Human, rat, - Western blot, 1-2μg/ml, Human, rat
Gene Name	KRT1
Gene Full Name	Keratin, type II cytoskeletal 1
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	Monoclonal anti cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. Monoclonal Anti Pan Cytokeratin (mixture) is a broadly reactive reagent, which recognizes epitopes present in most human epithelial tissues.
Immunogen	mixture of several monoclonal cytokeratin clones.
Contents	Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Purification	Ascites
Reconstitution	Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Concentration	Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.
Manufacturer - Research Category	Cytoskeleton/ECM, Intermediate Filaments, Microtubules, Signal Transduction
Protein Name	Keratin, type II cytoskeletal 1
Protein Function	May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK.
Subcellular Localization	Cell membrane. Located on plasma membrane of neuroblastoma NMB7 cells.
Description	Boster Bio Anti-PCK Antibody (Monoclonal, C-11+PCK-26+CY-90+KS-1A3+M20+A53-B/A2) catalog # MA1081. Tested in IHC, WB applications. This antibody reacts with Human, Rat.
Tissue Specificity	The source of this protein is neonatal foreskin. The 67-kDa type II keratins are expressed in terminally differentiating epidermis.
Sequence Similarities	Belongs to the intermediate filament family.
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-MA1081-datasheet.pdf

BOS-MA1081-safety-datasheet.pdf