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Anti-Peroxiredoxin 6/PRDX6 Antibody Picoband®

Anti-Peroxiredoxin 6/PRDX6 Antibody Picoband®

Item no.	BOS-PB9350
Manufacturer	Boster
Amount	100 ug/vial
Quantity options	100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Category	Oncology Metabolism Diabetes Cholesterol & Lipid Metabolism Antibodies Cell Biology Cell Status Cell Metabolism Immunohistochemistry Western Blot Immunocytochemistry Cardiovascular Research Thrombosis & Hemostasis Enzymes Fatty Acid Catabolism Oxidative Stress Primary Antibodies By Organ Lung Cancer Immunochemistry
Type	Antibody Polyclonal
Format	Lyophilized
Applications	WB, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<5 pg/ml
Sequence	Belongs to the AhpC/TSA family. Rehydrin subfamily.
Citations	1. Ambruso DR, et al. Peroxiredoxin 6 translocates to the plasma membrane during neutrophil activation and is required for optimal NADPH oxidase activity. Biochim Biophys Acta, 2012 Feb. 2. Chhunchha B, et al. Aberrant sumoylation signaling evoked by reactive oxygen species impairs protective function of Prdx6 by destabilization and repression of its transcription. FEBS J, 2014 Aug. 3. Guo HW, et al. Expression of peroxiredoxin 6 in gastric cancer and its clinical significance. Zhonghua Yi Xue Za Zhi, 2012 Sep 11.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Peroxiredoxin-6,1.11.1.15,1-Cys peroxiredoxin,1-Cys PRX,24 kDa protein,Acidic calcium-independent phospholipase A2,aiPLA2,3.1.1.-,Antioxidant protein 2,Liver 2D page spot 40,Non-selenium glutathione peroxidase,NSGPx,1.11.1.9,Red blood cells page spot 12,PRDX6,AOP2,KIAA0106
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	25 kDa
Calculated Molecular weight	25035 MW
Clonality	Polyclonal
Application Details	Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat Immunocytochemistry , 0.5-1μg/ml, Human
Gene Name	PRDX6
Gene Full Name	Peroxiredoxin-6
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	PRDX6 is also known as PRX, p29 or AOP2. The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H (2)O (2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
Immunogen	E.coli-derived human Peroxiredoxin 6 recombinant protein (Position: E15-P224). Human Peroxiredoxin 6 shares 90% and 91% amino acid (aa) sequence identity with mouse and rat Peroxiredoxin 6, respectively.
Contents	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Atherosclerosis, Cancer, Cancer Metabolism, Cardiovascular, Cell Biology, Heart Disease, Lipid Metabolism, Metabolism, Mitochondrial Markers, Mitochondrial Metabolism, Oxidative Stress, Pathways and Processes, Redox Metabolism, Signal Transduction, Vascular Inflammation
Protein Name	Peroxiredoxin-6
Protein Function	Involved in redox regulation of the cell. Can reduce H (2)O (2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
Subcellular Localization	Cytoplasm. Lysosome. Cytoplasmic vesicle. Also found in lung secretory organelles.
Description	Boster Bio Anti-Peroxiredoxin 6/PRDX6 Antibody Picoband® catalog # PB9350. Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Synthesized in numerous tissues (including tumors) and secreted into most extracellular body fluids, such as plasma, uterine fluid, saliva, gingival crevicular fluid, tears, seminal fluid, and milk.
Sequence Similarities	Belongs to the AhpC/TSA family. Rehydrin subfamily.
Manufacturer - Alias	Peroxiredoxin-6, 1.11.1.15, 1-Cys peroxiredoxin, 1-Cys PRX, 24 kDa protein, Acidic calcium-independent phospholipase A2, aiPLA2, 3.1.1.-, Antioxidant protein 2, Liver 2D page spot 40, Non-selenium glutathione peroxidase, NSGPx, 1.11.1.9, Red blood cells page spot 12, PRDX6, AOP2, KIAA0106
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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BOS-PB9350-datasheet.pdf

BOS-PB9350-safety-datasheet.pdf