« Back
Home /
Anti-alpha 1 Antitrypsin/SERPINA1 Antibody Picoband®

Anti-alpha 1 Antitrypsin/SERPINA1 Antibody Picoband®

Item no.	BOS-PB9354
Manufacturer	Boster
Amount	100 ug/vial
Category	Food Safety Proteins Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot Cardiovascular Research Heart Failure Myocardial Infarction Atherosclerosis Hypertension Primary Antibodies
Type	Antibody Polyclonal
Format	Lyophilized
Applications	WB, IHC
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<5pg/ml
Citations	1. Mixture-based combinatorial libraries from small individual peptide libraries: a case study on 1-antitrypsin deficiency.Chang YP, et al. Molecules, 2014 May 16. 2. Serpin peptidase inhibitor clade A member 1 is a biomarker of poor prognosis in gastric cancer.Kwon CH, et al. Br J Cancer, 2014 Nov 11. 3. Alpha 1-antitrypsin therapy mitigated ischemic stroke damage in rats.Moldthan HL, et al. J Stroke Cerebrovasc Dis, 2014 May-Jun.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Alpha-1-antiproteinase;Alpha-1-antitrypsin;Alpha-1-proteinase inhibitor;Serpin A1;Serpina1;
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	53 kDa
Calculated Molecular weight	46136 MW
Clonality	Polyclonal
Application Details	Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml, Mouse, Rat, By Heat Western blot, 0.1-0.5?g/ml, Mouse, Rat
Manufacturer - Gene Name	SERPINA1
Gene Full Name	Alpha-1-antiproteinase
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	SERPINA1 is also known as PI, A1A or AAT. The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.
Immunogen	E.coli-derived rat SERPINA1 recombinant protein (Position: K211-R411). Rat SERPINA1 shares 66% amino acid (aa) sequence identity with human SERPINA1.
Contents	Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category	Apoptosis, Cancer, Cancer Metabolism, Cardiovascular, Cell Biology, Intracellular, Kinases, Metabolism, Metabolism Processes, Pathways and Processes, Protease Inhibitors, Proteolysis/Ubiquitin, Response To Hypoxia, Serum Proteins
Protein Name	Alpha-1-antiproteinase
Protein Function	Inhibitor of serine proteases. The primary target is elastase, but also has a moderate affinity for plasmin and thrombin.
Subcellular Localization	Secreted.
Description	Boster Bio Anti-alpha 1 Antitrypsin/SERPINA1 Antibody Picoband® catalog # PB9354. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Plasma.
Sequence Similarities	Belongs to the semaphorin family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-PB9354-datasheet.pdf

BOS-PB9354-safety-datasheet.pdf