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Anti-Angiotensinogen/AGT Antibody Picoband® European Partner

Item no. BOS-PA1643
Manufacturer Boster
Amount 100 ug/vial
Category
Type Antibody Polyclonal
Format Lyophilized
Applications WB, IHC
Specific against Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Sensitivity >5000 cells
Citations 1. Abonia, J. P., Abel, K. J., Eddy, R. L., Elliott, R. W., Chapman, V. M., Shows, T. B., Gross, K. W. Linkage of Agt and Actsk-1 to distal mouse chromosome 8 loci: a new conserved linkage. Mammalian Genome 4: 25-32, 1993.
2. Arakawa, K., Minohara, A., Yamada, J., Nakamura, M. Enzymatic degradation and electrophoresis of human angiotensin I. Biochim. Biophys. Acta 168: 106-112, 1968.
3. Basso N, Terragno NA (December 2001). "History about the discovery of the renin-angiotensin system". Hypertension 38 (6): 1246–9.

ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Angiotensinogen;Serpin A8;Angiotensin-1;Angiotensin 1-10;Angiotensin I;Ang I;Angiotensin-2;Angiotensin 1-8;Angiotensin II;Ang II;Angiotensin-3;Angiotensin 2-8;Angiotensin III;Ang III;Des-Asp[1]-angiotensin II;Angiotensin-4;Angiotensin 3-8;Angiotensin IV;Ang IV;Angiotensin 1-9;Angiotensin 1-7;Angiotensin 1-5;Angiotensin 1-4;Agt;Serpina8;
Similar products AGT antibody, Aangiotensinogen(serpin peptidase inhibitor clade A member 8) antibody, AI265500 antibody, Alpha 1 antiproteinase antitrypsin antibody, Ang antibody, Ang I antibody, Ang II antibody, Ang III antibody, AngII antibody, Angiotensin I antibody, Angiotensin II antibody, Angiotensin III antibody, Angiotensin-3 antibody, Angiotensinogen(PAT) antibody, Angiotensinogen antibody, ANGT_HUMAN antibody, ANHU antibody, ANRT antibody, Des-Asp-angiotensin II antibody, FLJ92595 antibody, FLJ97926 antibody, MGC105326 antibody, PAT antibody, Pre angiotensinogen antibody, Serine(or cysteine) proteinase inhibitor antibody, Serpin A8 antibody, Serpin peptidase inhibitor clade A member 8 antibody, SERPINA8 antibody
Available
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
55 kDa
Calculated Molecular weight
51990 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5?g/ml, Mouse

Immunohistochemistry(Paraffin-embedded Section), 2-5 ?g/ml, Mouse
Manufacturer - Gene Name
AGT
Gene Full Name
Angiotensinogen
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
AGT (ANGIOTENSINOGEN), also called SERPINA8, is an alpha-2-globulin that is produced constitutively and released into the circulation mainly by the liver. ATG is a member of the serpin family, although it is not known to inhibit other enzymes, unlike most serpins. Angiotensinogen is also known as renin substrate. The AGT gene is mapped on 1q42.2. And the human angiotensinogen gene contains 5 exons. The expression of AGT and enzymes required for its conversion to angiotensin II in human adipose tissue. Western blot analysis showed a distinct band of expected size of the angiotensinogen protein (61 kD) in isolated adipocytes. The more pronounced AGT increase in TT subjects resulted in similar plasma renin activity at a lower plasma active renin concentration, with a higher plasma renin activity/active renin ratio.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of mouse Angiotensinogen, identical to the related rat sequence.
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Cardiovascular, G Protein Signaling, Signal Transduction, Signaling Pathway
Protein Name
Angiotensinogen
Protein Function
Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
Subcellular Localization
Secreted.
Description
Boster Bio Anti-Angiotensinogen/AGT Antibody catalog # PA1643. Tested in IHC, WB applications. This antibody reacts with Mouse.
Tissue Specificity
Expressed by the liver and secreted in plasma.
Sequence Similarities
Belongs to the ku70 family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug/vial
Available: In stock
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