Anti-CREB-BP Antibody

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Polyclonal

CREBBP

Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers.
Zoi Lygerou, Nucleic Acids Res., Feb 1994; 22: 5332 - 5340.
Karsten Grote, J. Biol. Chem., Dec 2004; 279: 55675 - 55681.
Kumi Nagamoto-Combs, J. Biol. Chem., Feb 1997; 272: 6051.
Stephen J. Elliman, Isaac, J. Biol. Chem., Jan 2006; 281: 16 -19

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

1 mg/ml

Cytoplasm. Nucleus. Recruited to nuclear bodies by SS18L1/CREST. In the presence of ALX1 relocalizes from the cytoplasm to the nucleus.

Boster Bio Anti-CREB-BP Antibody (Catalog # A00205). Tested in WB, IHC, IF applications. This antibody reacts with Human.