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Anti-Interferon gamma Biotinylated IFNG Antibody

Anti-Interferon gamma Biotinylated IFNG Antibody

Item no.	BOS-A00393-Biotin
Manufacturer	Boster
Amount	100 ug/vial
Category	Neuroscience Neuroinflammation Antibodies Cell Biology Cell Culture Cytokines ELISA Primary Antibodies
Type	Antibody Polyclonal
Format	Lyophilized
Applications	ELISA
Specific against	Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Biotin
Citations	Nanba D, Higashiyama S (February 2004). "Dual intracellular signaling by proteolytic cleavage of membrane-anchored heparin-binding EGF-like growth factor". Cytokine Growth Factor Rev. 15 (1): 13–9. Jin K, Mao XO, Sun Y, Xie L, Jin L, Nishi E, Klagsbrun M, Greenberg DA (July 2002). "Heparin-binding epidermal growth factor-like growth factor: hypoxia-inducible expression in vitro and stimulation of neurogenesis in vitro and in vivo". J. Neurosci. 22 (13): 5365–73. Fen, Z., Dhadly, M. S., Yoshizumi, M., Hilkert, R. J., Quertermous, T., Eddy, R. L., Shows, T. B., Lee, M.-E. Structural organization and chromosomal assignment of the gene encoding the human heparin-binding epidermal growth factor-like growth factor/diphtheria toxin receptor. Biochemistry 32: 7932-7938, 1993.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Interferon gamma; IFN-gamma; IFNG
Available
Specificity	No cross reactivity with other proteins.
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	39 kDa
Clonality	Polyclonal
Application Details	ELISA Detection (Matched Antibody Pair), 0.1-0.5?g/ml
Manufacturer - Gene Name	IFNG
Gene Full Name	interferon gamma
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	Interferon-gamma (IFN-gamma) is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues. The production of IFN-gamma, which is under genetic control, can influence the development of fibrosis in lung allografts. IFN-gamma is also produced by natural killer (NK) cells and most prominently by CD8 cytotoxic T cells, and is vital for the control of microbial pathogens. Interferon gamma is believed to be crucial for host defence against many infections. Genetically determined variability in IFN-gamma and expression might be important for the development of tuberculosis. IFN-gamma activates human macrophage oxidative metabolism and antimicrobial activity. In addition to having antiviral activity, IFN-gamma has important immunoregulatory functions. IFN-gamma plays an important role in the control of neointima proliferation.
Immunogen	E. coli-derived rat Interferon gamma recombinant protein (Position: M1-C156).
Contents	Each vial contains 4 mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, 0.05 mg NaN₃.
Reconstitution	Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category	Cancer, Cytokines, Immunology, Innate Immunity, Interferons, Signaling Pathways, Stem Cells, TGF Beta, Tumor Immunology
Protein Name	Interferon gamma
Protein Function	Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Description	Boster Bio Anti-Interferon gamma Biotinylated IFNG Antibody catalog # A00393-Biotin. Tested in ELISA applications. This antibody reacts with Rat.
Tissue Specificity	Released primarily from activated T lymphocytes.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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BOS-A00393-Biotin-datasheet.pdf

BOS-A00393-Biotin-safety-datasheet.pdf