Anti-CDA Antibody Picoband™

Primary Antibodies, Rabbit Polyclonal Antibodies

Boster Bio Anti-CDA Antibody Picoband™ catalog # A01578-1. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Cytidine deaminase is an enzyme that in humans is encoded by the CDA gene. This gene is mapped to 1p36.12. It encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.

Western blot, 0.1-0.5μg/ml
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

A synthetic peptide corresponding to a sequence at the N-terminus of human CDA, which shares 63% amino acid (aa) sequence identity with both mouse and rat CDA.

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

16 kDa

Cytosol, Extracellular region, Ficolin-1-rich granule lumen, Secretory granule lumen, Tertiary granule lumen.