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Anti-Human RAB27A DyLight® 488 conjugated Antibody

Anti-Human RAB27A DyLight® 488 conjugated Antibody

Manufacturer	Boster
Category	Antibodies Cell Biology Cytoskeleton Flow Cytometry Primary Antibodies small GTPases Rab Subfamily
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Isotype	IgG
Format	Liquid
Applications	FC
Amount	100 ug/vial
Host	Rabbit
Item no.	BOS-A01608-Dyl488
Targets	RAB27A
Conjugate/Tag	DyLight 488
eClass 6.1	32160702
eClass 9.0	32160702
Available
Manufacturers Product Category	Primary Antibodies, Rabbit Polyclonal Antibodies
Manufacturers Research Category	Signaling Pathway, Small G Proteins, Vesicle Transport
Short Description	Boster Bio Anti-Human RAB27A DyLight® 488 conjugated Antibody catalog # A01608-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-Human RAB27A DyLight® 488 conjugated Antibody catalog # A01608-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Background	Ras-related protein Rab-27A is a protein that in humans is encoded by the RAB27A gene. The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
Gene Name	RAB27A
Application Details	Flow Cytometry, 1-3μg/1x10⁶ cells
Clonality	Polyclonal
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Contents	Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Immunogen	E. coli-derived human RAB27A recombinant protein (Position: L98-K216).
Cross-reactivity	No cross-reactivity with other proteins.
Storage	At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Gene Full Name	RAB27A, member RAS oncogene family
Protein Function	Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.
Subcellular Localization	Membrane; Lipid-anchor. Melanosome.
Tissue Specificity	Found in all the examined tissues except in brain. Low expression was found in thymus, kidney, muscle and placenta. Detected in melanocytes, and in most tumor cell lines examined. Expressed in cytotoxic T-lymphocytes (CTL) and mast cells.

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Amount: 100 ug/vial

available

Delivery expected until 5/30/2024