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Anti-CREBZF/Zhangfei Antibody

Anti-CREBZF/Zhangfei Antibody

Item no.	BOS-A07952
Manufacturer	Boster
Amount	100 ul
Category	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Type	Antibody
Format	Liquid
Applications	WB, IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CREB/ATF bZIP transcription factor;Host cell factor-binding transcription factor Zhangfei;HCF-binding transcription factor Zhangfei;CREBZF;ZF;
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	37134 MW
Clonality	Polyclonal
Application Details	Western blotting: 1:500~1:3000 Immunofluorescence: 1:100~1:500
Manufacturer - Gene Name	CREBZF
Gene Full Name	CREB/ATF bZIP transcription factor
Background	Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells. Lu R., Nucleic Acids Res. 28:2446-2454(2000). The MGC Project Team, Genome Res. 14:2121-2127(2004). Misra V., J. Biol. Chem. 280:15257-15266(2005).<
Immunogen	Synthesized peptide derived from internal of human CREBZF.
Contents	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Protein Function	Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1- dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells.
Subcellular Localization	Nucleus. Colocalizes in promyelocytic leukemia protein nuclear bodies (PML-NB) with CREB3 and HCFC1.
Short Description	Boster Bio Anti-CREBZF/Zhangfei Antibody (Catalog # A07952). Tested in WB, IF applications. This antibody reacts with Human, Mouse.
Description	Boster Bio Anti-CREBZF/Zhangfei Antibody (Catalog # A07952). Tested in WB, IF applications. This antibody reacts with Human, Mouse.
Tissue Specificity	In adults, expressed most abundantly in heart, liver and skeletal muscle, moderately abundant in kidney and pancreas, and barely detectable in lung. In fetal tissues, expressed most abundantly in kidney and very low amounts in heart, lung and liver.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A07952-datasheet.pdf

BOS-A07952-safety-datasheet.pdf