Anti-SOX2 Rabbit Monoclonal Antibody

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

34310 MW

WB 1:1000-2000
IHC 1:50-200
ICC/IF 1:50-200

Transcription factor SOX-2

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Cell Type Marker, Developmental Biology, Domain Families, Embryogenesis, Embryonic Stem Cells, Epigenetics and Nuclear Signaling, Germ Cell Markers, Germline Stem Cells, Hlh/Leucine Zipper, Intracellular, Neural Signal Transduction, Neurogenesis, Neurology Process, Neuroscience, Reproduction, Stem Cells, Surface Molecules, Transcription

Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

Boster Bio Anti-SOX2 Rabbit Monoclonal Antibody catalog # M00105-1. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.