Anti-FMRP FMR1 Rabbit Monoclonal Antibody

Rabbit Monoclonal Antibodies

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

71174 MW

WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200

Fragile X mental retardation protein 1

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Chromatin Binding Proteins, DNA/RNA Binding, Epigenetics and Nuclear Signaling, Neural Signal Transduction, Neurology Process, Neuroscience

Translation repressor. Component of the CYFIP1-EIF4E- FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA- binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly (G), binds moderately to poly (U) but shows very little binding to poly (A) or poly (C).

Boster Bio Anti-FMRP FMR1 Rabbit Monoclonal Antibody catalog # M00192. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.