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Anti-ARF6 Rabbit Monoclonal Antibody

Anti-ARF6 Rabbit Monoclonal Antibody

Item no.	BOS-M00927
Manufacturer	Boster
Amount	100 ul
Category	Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, ICC
Clone	AOFF-1
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	1.0 IU/L
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	ADP-ribosylation factor 6;ARF6;
Available
Manufacturer - Category	Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	120-150 kDa
Calculated Molecular weight	20082 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:2000 ICC/IF 1:50-1:200
Manufacturer - Gene Name	ARF6
Gene Full Name	ADP-ribosylation factor 6
Immunogen	A synthesized peptide derived from human ARF6
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Protein Trafficking, Signal Transduction, Vesicle Transport
Protein Name	Glycogen synthase kinase-3 beta (gsk3b)
Protein Function	GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling. Required for normal completion of mitotic cytokinesis. Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers. May also modulate vesicle budding and uncoating within the Golgi apparatus. Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension. Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase.
Subcellular Localization	Golgi apparatus. Cell membrane; Lipid- anchor. Endosome membrane; Lipid-anchor. Recycling endosome membrane; Lipid-anchor. Cell projection, filopodium membrane; Lipid-anchor. Midbody. Cytoplasm. Cleavage furrow. Distributed throughout the cytoplasm during metaphase. Transiently detected at the ingressing cleavage furrow during mitotic cytokinesis. Recruited to the midbody at later stages of cytokinesis; this requires interaction with KIF23 (By similarity). Recruited to the cell membrane in association with CYTH2 and ARL4C. Colocalizes with DAB2IP at the plasma membrane and endocytic vesicles.
Description	Boster Bio Anti-ARF6 Rabbit Monoclonal Antibody catalog # M00927. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Ubiquitous, with higher levels in heart, substantia nigra, and kidney.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M00927-datasheet.pdf

BOS-M00927-safety-datasheet.pdf